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The TEM images in Fig. 5 show that some cavities and holes form after modification consistent with the increase of pore volumes.
However the molecular mass range of XylA determined by SDS-PAGE from P. pastoris was 153 to 165 kDa indicating differences in post-translational modification consistent with the predicted glycosylation sites.
The Cdx2 promoter, active in the trophectoderm and silent in the ICM, shows the opposite pattern of modification, consistent with its transcriptional status (Fig. 2).
In contrast, most adenosines in helix 45 and domain I were largely protected from chemical modification, consistent with a stem structure.
The primary IPD ratio peaks for the 5caC sample again fell at the +2 position relative to the modification, consistent with the results obtained from the synthetically derived samples.
The term homology at the character level is operationally used in the molecular community as descent from a common ancestor with modification, consistent with the definition of homology for genes given above.
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"We are working hard to make design modifications consistent with the Landmarks Preservation Commission and public comments," Stephen Benjamin, a Dermot principal, said last week in a statement, "and are hopeful that the design will be even more successful than our previous submission".
Analysis of the unfolded variant by FPOP MS shows oxidative modifications consistent with the species adopting a solution conformation with a high degree of solvent accessibility.
Experimental studies showed that both ABCA4 and COL2A1 show isoform-specific epigenetic modifications consistent with imprinting.
Only K562 showed increased levels of histone modifications consistent with the activity of the enhancer at +51 extending to +50.
These results demonstrate that the transition from reduced expression to gene inactivation is associated with a shift from activating to repressive histone modifications consistent with epigenetic silencing.
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