Sentence examples for modification complex from inspiring English sources

JARID2 is a component of chromatin modification complex PRC2 in embryonic stem cells and is required for multilineage differentiation.

It is possible that SirT1 works in the context of a larger epigenetic modification complex, as demonstrated in the murine Polycomb repressive complex 4 (PRC4) [ 24].

HOTAIR can also interact with a second histone modification complex, the LSD1/CoREST/REST complex, which coordinates the targeting of PRC2 and LSD1 to chromatin for coupled histone H3K27 methylation and K4 demethylation [ 22].

Monomeric actin is a core component of the INO80 and SWR chromatin remodeling complexes and the NuA4 histone modification complex, and our results suggest these complexes may be sensitive to actin stoichiometry.

In addition, miRNAs directly and abundantly target a core histone modification complex (Hdac4-Mef2c-Mef2d, http://www.nlmi.nih.gov/gene/97599759) (Fig.  7), including Mef2c (myocyte enhancer factor 2C), which was targeted by the top over-expressed miRNA clusters including miR-290-295 and miR-302 cluster (Fig.  7).

Therefore, HOTAIR can serve as a scaffold for multiple histone modification complexes.

This site is thought to recruit transcription factors that suppress gene expression by activating repressive histone modification complexes.

Menin is known to serve as both an activator and repressor of transcription via integration of different chromatin modification complexes.

Both W and Crooks are restriction minus as they lack hsdMRS, mcrBC and mrr, which encode the restriction modification complexes.

Interestingly, two recent studies linking the function of the NuA4 complex to other chromatin modification complexes, including SWR1-C, highlight a coordinating role for EAF1 [ 40, 41].

Those genes are mainly from families encoding components of the proteasome/protein modification complexes, signal transduction machinery, ribosomes and transcription factor complexes.