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During knowledge acquisition, given a case x that requires an NRDR knowledge base to be modified, the modification can occur in a number of places.
This posttranslational modification can occur on either lysine or arginine residues in the tails of histones 2, 3, and 4, with lysines being either mono-, di-, or tri-methylated and arginines being mono-methylated or symmetrically or asymmetrically di-methylated [7].
It is possible that post-translational modification can occur on rTFF1/BC.
Histone modification can occur by acetylation, methylation, ubiquitylation, phosphorylation or sumoylation.
PmrA-dependent modification can occur on each of the three distinct LPS domains, namely, lipid A, core polysaccharide, and O-antigen chain.
Many of these studies have thus provided vast in silico libraries of modified proteins and the sites at which modification can occur [ 7- 13].
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All well and good, but the new CRISPR-Cas9 technology radically accelerates the time period in which modifications can occur and makes transgenic tinkering so much easier and more efficient.
It is apparent that evolutionary cell modifications can occur in response to relatively rapid changes in environment over periods ranging from days to months rather than the thousands of years considered in most evolutionary modifications.
Further modifications can occur by e. g. hydroxylases (Dickson and Lester, 2002).
Such chemical modifications can occur during bioprocesses and storage conditions of the commercial HSA solutions, resulting in heterogeneous solutions for infusion.
Many modifications can occur: freshly detached particles are different from particles that have been in contact with biological tissues for some time [23], and the debris may be not only fragments of UHMWPE but fragments of an oxidized, lower molecular mass polyethylene [24].
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