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Genetically modifying eggs, sperm, and zygotes ('germline' modification) can impact on the entire body of the resulting individual and on subsequent generations.
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These results may provide exciting future research opportunities if the structural modifications can impact the bioavailability of entrapped materials.
Regardless of how this controversy is ultimately resolved, both modifications can impact miRNA processing and activity profoundly.
Functional and structural studies have shown that rRNA modification defects can impact on translation rates and ribosome integrity.
Our findings indicate that the chromatin modifications context can impact the catalytic activity of KDM5A through modulation of the degree to which PHD1 is bound by a ligand.
Recent studies have suggested that such modifications in treatment can impact on the time to recovery and these changes may be associated with improvements in various HRQOL measures [ 2, 3, 5, 8].
Risk of unauthorized disclosure or modification of corporate data can impact in different ways, including affecting operations, the public image and/or the firm's legal/compliance exposure.
However, chemical modification of the target can impact binding and requires suitable functional groups for conjugation.
Previous work has shown that modification of lignin hydrophobicity can impact interaction of cellulases with lignin [ 25, 29, 51].
Such changes, which are considered as modifications in environmental factors, can impact the system response.
So far studies identified that changes in built environment and modifications in space design can impact residents and offenders perceptions of criminality.
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