Sentence examples for modification by sumoylation from inspiring English sources

We found that post-translational modification by sumoylation affects both FOXL2 metabolism and activity.

Posttranscriptional protein modification by SUMOylation plays an important role in tumor development and progression.

Thus, plant post-translational modification by SUMOylation is of fundamental importance in modulating numerous signaling pathways.

Post-transcriptional modification by SUMOylation is involved in numerous cellular processes including human spermatogenesis.

Posttranslational protein modification by SUMOylation is a fundamentally important regulatory mechanism in nearly all cell pathways (Hay, 2005).

This might apply as well to TDG, given its propensity to posttranslational modification by SUMOylation (Hardeland et al. 2002), ubiquitylation (Hardeland et al. 2007), phosphorylation (Um et al. 1998), and acetylation (Tini et al. 2002).

While little is known about this possibility in plants, mammalian orthologs of plant subunits encoded by gene families are known to be subject to modification by phosphorylation, SUMOylation, ubiquitination, and arginine methylation [ 52].

Modification of proteins by SUMOylation is transient and dynamic, due to the rapid turnover of conjugated species by SUMO proteases.

(157) Modification of NOP5/58 by SUMOylation and phosphorylation is shown in Figure 6.

Given that sumoylation plays an essential role in regulating mitotic proteins [ 23], we asked whether Kif18A was modified by sumoylation and whether the modification affected its activity in mitosis.

This does not represent a general modification of the availability of the PDZ domain in RIM1α by SUMOylation, given that the interaction between ELKS1b/2 and RIM1α (also via the PDZ domain) was not affected by SUMOylation.