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There was a trend toward mild effect measure modification by study phase, but this was not statistically significant.
Effect modification by study was also tested.
The effect modification by study characteristics was explored using meta-regression.
However, in our a priori subgroup analyses, there was no effect modification by study quality.
In addition, we observed effect modification by study follow-up period in this meta-analysis.
We also used multiplicative interaction terms to test effect modification by study follow-up period (original vs. extended).
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In the presence of heterogeneity, sensitivity analyses were performed to evaluate effect modification by study-level characteristics including study design, GDM diagnostic criteria, physical activity measures (METs vs. frequency only; number of quantiles), and country of study (19).
Yet, adjustment for intensity of differences in healthfulness had little effect on pooled price differences, and meta-regression revealed no significant effect modification by intensity, study location or study type.
There was an indication of effect modification by several study conditions.
The increase (decrease) of the selected bands intensity in the Raman spectrum of DNA after modification by the studied naphthoquinones is summarized in Table 1.
In addition, we determined whether a specific methyl-CpG binding protein, MeCP2, is necessary for the inactive X histone modification pattern by studying Rett syndrome cells which are deficient in MeCP2 function.
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