Sentence examples for modification by methylation from inspiring English sources
The flavonoid modification by methylation provides a greater stability and improved pharmacokinetic properties.
Stratified analyses were conducted to evaluate effect modification by methylation efficiency on the association between BCC and iAs exposure.
POG-modified Tβγ was further subjected to modification by methylation at the C-terminal carboxyl group, which copies a complete set of the known posttranscriptional modifications of Tβγ.
The identification of altered transcriptional and translational silencing by microRNAs and epigenetic modification by methylation in tumours has showed a layer of additional intricacy to the regulation of gene expression in different tumour types.
In eukaryotic organisms, post-translational protein modification by methylation, phosphorylation, acetylation, glycosylation, or ubiquitination by Ub (ubiquitin) and Ubls (ubiquitin-like proteins), play important roles in diverse cellular regulatory processes [ 1, 2].
These findings suggest that chromatin remodeling, such as histone modification by methylation or acetylation, is an important factor for ATRA sensitivity in MLL-rearranged AML, and the epigenetic priming of RA pathway is necessary for the differentiation therapy in MLL-rearranged AML.
Besides the alternative removal of the methionine, the N-terminal peptides of H2AFZ were differentially modified and contained between three to five different modifications by methylation, acetylation/trimethylation, phosphorylation and ubiquitination (Figure 2).
We assessed whether histone modifications by methylation or acetylation influence the observed training effects of MDP and flagellin.
Three mechanisms are mainly responsible for acquiring resistance to MLS antibiotics in staphylococci: (1) target site modifications by methylation or mutation; (2) active efflux of antibiotics; or (3) inactivation of antibiotics.
We did not find changes in the methylation degree of all genes affected by CoQ10 deficiency, suggesting that other modalities of gene regulation are responsible, including epigenetic mechanisms such as histone modifications by methylation and acetylation, or even DNA methylation in CpG islands other than those studied here.
Effect modification by DNA methylation.
