Sentence examples for modification by many from inspiring English sources

However, most guidelines, regardless of their source, are little more than general advice, applicable only under certain clinical circumstances and subject to modification by many possible medical complications, both of which the physician must determine for each patient.

Prenylation is a posttranslational modification required by many different kinds of proteins to ensure their proper trafficking and localization.

In vivo, this posttranslational modification is modulated by many kinases and phosphorylated sites are clustered in the accessible head and/or tail domains, probably because of limited kinase access along the coiled coil rod domain [ 22].

Histone modifications are catalyzed by many enzymes such as histone acetyltransferases (HATs), histone deacetylases (HDACs), histone methyltransferases (HMTs), and histone demethylases (HDMs).

Unlike conventional methods used for the characterization of PTMs such as the enrichment strategies either with antibodies or immobilized resin, lectin's binding strategy, or enzymatic based techniques, 2-DE offers an analytical tool with high resolution and high reproducibility by taking the advantage of the well known change in pI and MW induced by many modifications [ 41].

Cytosine DNA methylation is an epigenetic modification that is shared by many eukaryotic organisms.

Epigenetic modifications have been associated by many studies with several types of diseases and metabolic dysfunctions.

He recognizes that specializations for particular lifestyles reflect modifications of traits shared by many animals.

Chemical modification and inactivation of aminoglycosides by many different enzymes expressed in pathogenic bacteria are the main mechanisms of bacterial resistance to these antibiotics.

ERG-dependent chromatin modification has also been found by many Chip-Seq studies that also revealed that AR binding is significantly altered in ERG-expressing cells [ 4– 6].

Many proteins are targeted for covalent modification by SUMO, which consequently modulates many cellular processes [2] [4].