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This might reflect the presence of effect modification by characteristics that varied across studies (Bellinger 2009) or to methodological factors such as differences in the amount of exposure measurement error, which usually biases estimation toward the null (Grandjean et al. 2004).
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Objectives: We examined mortality from heat waves in seven major Korean cities for 2000 through 2007 and investigated effect modification by individual characteristics and heat wave characteristics (intensity, duration, and timing in season).
In addition, we estimated effects of heat wave characteristics and effects according to cause of death and examined effect modification by individual characteristics for Seoul.
Case-crossover desinherentlyntly controls for fixed individual characteristics like gender and race, and allows the evaluation of effect modification by individual characteristics.
Effect modification by patient characteristics was investigated.
There was no evidence of effect modification by tumor characteristics.
We also examined regional differences in effects and effect modification by individual characteristics.
The effect modification by study characteristics was explored using meta-regression.
The aforementioned models will be extended to study effect modification by patient characteristics.
In addition, we examined effect modification by city characteristics by entering them as predictor variables in the meta-regression.
We also examined regional differences in effect estimates by estimating effects for different cities and investigated effect modification by individual characteristics for Seoul.
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