If the modification was major or if the indicator was judged uncertain, it was resubmitted for a second round of validation.
DNA replication timing, 3D chromosomal conformation, and several histone modifications are major covariates of position effects.
Although it is generally undisputed that bifurcating speciation events and descent with modifications are major forces of evolution, there is a growing belief that reticulate events also have a role to play.
This result is in line with a recent study that two kingdom-specific tRNA modifications are major contributors that separate archaeal, bacterial, and eukaryal genomes in terms of their tRNA gene composition.
Post-translational modifications of histones are major players in epigenetic control.
Surface micro/nano structures and materials modification are the major methods to enhance the output performance of triboelectric nanogenerator (TENG).
Chromatin remodeling and histone modification are two major epigenetic mechanisms that alter nucleosome structure to regulate gene expression.
These results suggest that changes in adenine nucleotides, rather than direct oxidative modification, are the major drivers of AMPK activation during oxidative stress.
Histone modification and DNA methylation are major epigenetic mechanisms [ 20].
Both steps are major modifications of earlier Bush administration pronouncements.
