Sentence examples for modification and regulatory from inspiring English sources

Since transcriptomics data do not necessarily reflect enzyme activities (due to post-transcriptional modification and regulatory effects), we use the results from the analysis of the expression data only as indicator for the activity of the respective reaction rather that definite values.

This suggests that high levels of H3-K27me3 may lock in the repressed state of Sox1 in NS cells while lower levels may still allow its up-regulation at day 8, confirming that the H3-K27me3 status contributes to transcriptional output only in the context of other histone modifications and regulatory inputs.

The acceleration of expression divergence is probably driven by functional redundancy created by the first round of whole genome duplication and facilitated by epigenetic modifications and regulatory mutations.

Metazoan gene expression is controlled through the complex interplay of transcription factors, histone modifications and regulatory elements [ 1, 2] in three-dimensional nuclear space [ 3].

These epigenetic influences include DNA methylation, post-translational histone modifications and regulatory noncoding RNAs, all of which can have profound effects on gene expression that control cell phenotype and function [ 48].

84 These types of SIRT1 activity regulations (both posttranslational modifications and regulatory complex formation) have not been thoroughly explored in skeletal muscle, making it an important direction for future research.

Monkey King insertions potentially regulate gene expression and genome evolution through epigenetic modification and new regulatory motif production.

Using regulatory and chromatin structure data, such as the results from the ENCODE project [ 19], studies have shown that certain genomic annotations such as chromatin structure, DNA methylation, histone modification and other regulatory regions, are enriched for TAVs [ 18, 20– 25].

Metagenomics could and should be developed as well as the in-depth analysis of DNA methylation, histone modification, and the regulatory effects of small RNA, and transposon dynamics in adaptation and speciation to evaluate genome-wide adaptive divergence (Nevo 2009, and references therein).

DNA methylation detection, EMSA analysis, identification of a Monkey King-related miRNA, and transgenic experiments suggested that Monkey King insertions could regulate gene expression and genome evolution in the Brassicaceae family in a variety of ways, such as epigenetic modification and new regulatory motif production.

This may be a complex network of positive and negative regulatory loops, operating through transcription factor networks, epigenetic (DNA and chromatin) modifications, and miRNA regulatory networks.