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The most important ones are DNA methylation, histone modification, and noncoding RNAs, most of which is known from animal and cell culture studies [7].
These pathways, as currently understood, include DNA methylation, histone covalent modification, and noncoding RNA expression.
Additional regulatory mechanisms, involving DNA methylation, histone modification and noncoding RNAs, are likely to contribute to these processes.
Major forms of these changes are DNA methylation, histone modification, and noncoding RNAs (ncRNAs) (Rivera and Bennett 2010).
Epigenetic mechanisms (e.g., DNA methylation, chromatin modification, and noncoding RNAs) have been suggested to regulate the OA-specific genes responsible for cartilage degradation (Hashimoto et al., 2009).
Specifically, alcohol-induced changes in DNA methylation, histone modification, and noncoding RNAs may alter the expression patterns of numerous genes important for neurodevelopment and behavior.
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Many motif-finding methods would benefit from the alignment referencing provided by the HMM's scaffolding of annotation across coding and noncoding regions.
The thirty loci used in this study differ in the proportion of synonymous, replacement and noncoding sites.
Listed for each series (PT series SNP summary ) are the number of filtered ('Materials and methods') coding and noncoding SNPs.
These databases contain the chromosome sizes, genomic DNA and a set of reference gene models and noncoding RNAs.
Coding and noncoding RNAs indicated similar ratios of downregulated species, while they showed diversity of upregulated species).
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