Sentence examples for modification and initial from inspiring English sources
Refinement of heavy atom positions, density modification and initial SpGH38 model building was conducted with RESOLVE [59].
Substructure solution, phasing, density modification and initial model building was performed with SOLVE and RESOLVE [48], [49] on the primitive orthorhombic crystal form.
The substructure determination, phasing, density modification and initial automatic model building were all performed by using the AutoSol Wizard of Phenix[44].
In all cases, initial phase calculations, electron density map modification, and initial model building were done using the HKL 3000 program (Minor et al. 2006).
Experimental phasing was performed with AutoSol in the PHENIX suite, using Phaser to calculate experimental phases and RESOLVE for density modification and initial model building, yielding interpretable density in the experimental map.
Greater sensitivity to modification (Mitas 1997) and initial nuclear magnetic resonance (NMR) data (Zheng et al. 1996) suggested that the adenine bases in CAG repeat hairpins might be extrahelical.
In summary, the starting point HTS hit was optimised for potency against PknB, and initial modifications showed promising gains in enzyme binding affinity but little or no cellular activity against M. tuberculosis.
More significantly, zircon ages and Hf isotopes imply that this lower crust had a complex history of accretion and modification, including initial growth at 3.0 4.0 Ga and 2.5 2.7 Ga, conversion to the dominant granulitic assemblages in the Early Paleoproterozoic (ca 2.3 Ga), modification or metamorphism in the Late Paleoproterozoic (1.8 2.0 Ga) and possibly slight heating in Neoproterozoic time.
SHELXC and SHELXD [57] were used for locating selenium sites and initial density modification with autoSHARP [58].
The key-genes found here are responsible for the phase 1 of xenobiotic metabolism, when an initial modification and activation of typically lipophylic xenobiotics occur [ 29].
Adsorption modification of initial silica and CeO2 ZrO2 SiO2 nanooxides was conducted with poly (dimethylsiloxane) due to the formation of hydrogen bonds ≡ MiO H···O(Si(CH3 2 2 (where M = Si, Ce, or Zr, i = 1 or 2) between the oxygen atoms in the PDMS polymer chain and hydrogen atoms of the surface hydroxyls (–OH) of the oxide particles.
