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FAIRE, histone modification and histone H3/H2B enrichments/depletions were interpreted based on visualizations of data plots.
The cancer microenvironment may thus influence epigenetic regulation of cancer-related gene expression by DNA modification and histone modification.
Three groups, including "Chromatin binding," "Histone modification," and "Histone acetyltransferase complex," relate to gene regulation at the level of chromatin.
External environment has been noted to affect the expression of genes by impacting on DNA methylation, protein modification and histone acetylation [ 1, 50].
This showed in cohort III an association between high levels of WRAP53 β and of a number of processes involved in the DNA damage response, including DNA repair, chromatin architecture, histone modification and histone binding (n=241; Figure 2a).
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The greatest variation in DNMT, histone modification and histone-modifying enzyme expression was observed between human embryos beginning at the four- to eight-cell stages, which we attributed, at least in part, to differences between single cells within the same embryo.
Different aspects of learning, memory, and cognition are regulated by epigenetic mechanisms such as covalent DNA modifications and histone post-translational modifications.
Proteomic tools allow the discovery of novel histone modifications and histone codes on histone tails.
Also, histone modifications and histone variants are often associated with distinct biological functions.
Histone modifications and histone variants are of importance in many biological processes.
These findings predominately included terms associated with epigenetic functions including covalent chromatin modifications and histone acetylation.
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