Sentence examples for modification and found from inspiring English sources

Finally, we also analyzed the H3K9me2 modification and found no enrichment on tGgIdas compared with tGgDId (Supplementary Fig. S1).

Several studies have examined effect modification and found that people carrying variants of oxidative stress-related genes are differentially susceptible to air [ 12- 16, 16, 48].

A recent study examined factors associated with ARV discontinuation or modification and found women had a higher hazard for short-term toxicity [ 55].

The Cache County Study [ 9, 20], the Canadian Study for Health and Aging (CSHA) [ 8], and the Rotterdam Study [ 7] adjusted for APOE and tested for effect modification and found none.

For each cell line, we estimated the number of CGIs containing at least one PS of histone modification and found, on average, 15478, 11903 and 10182 CGIs containing PSs of H3K4me3, H3K27ac and H3K36me3, respectively.

We used mass spectrometry to identify novel histone modifications and found an uncharacterized acetylation site on histone H3 lysine 64 (H3K64ac).

As an example, Egelhofer and colleagues tested over 200 commercially available antibodies raised to different histone modifications and found that more than 25% were not strictly specific to the modification advertised.

In addition, we mapped cytosine modification quantitative trait loci (mQTL) to investigate the genetic architecture of cytosine modifications, and found significant enrichment of mQTL for trait-associated GWAS loci in addition to eQTL (12, 13), highlighting the potential relevance of using mQTL as a functional annotation approach.

We further explored the overlaps of EIs with other histone modifications, and found that EIs highly overlaps with H3K4me3 (Enrichment up to 5.3) and H3K9ac (Enrichment up to 3.3), but less enrich for H3K27me3 (Enrichments from 1.7 to 2.2) and H3K36me3 (Enrichments from 0.7 to 2.1).

Under such conditions (and in the same cells), we compared the CCR2 modification rate and found higher off-target activity within this locus after plasmid-directed ZFN production.

De Hemptinne et al. [12] investigated the role of all four cysteines in NO-mediated modification of Glo1 and found that replacement of Cys61 by exchange with alanine did not prevent from NO-modification after GSNO treatment, while the Cys139 > Ala mutant, was impaired for NO-mediated modification.