Sentence examples for modification and chromatin from inspiring English sources

Silencing of genes has a complex mechanism, which involves methylation of DNA, histone modification and chromatin remodeling.

Thus, we speculate that the TETs-OGT crosstalk not only help OGT to raise in chromatin, but also regulates gene transcription by affecting histone modification and chromatin structure.

In fact, sequencing data has revealed that mutations exist in genes involved in nearly all aspects of epigenetics, including DNA methylation, covalent histone modification, and chromatin remodeling (Fig. 2).

Taken together, the changes in the expression of genes involved in DNA modification and chromatin structure demonstrate that the genome is undergoing rapid and dynamic changes that will greatly alter transcription factor accessibility.

These early enhanceosomes facilitate epigenetic modification and chromatin remodeling.

These results stress the importance of histone modification and chromatin remodeling in DDR.

Here we used histone modification and chromatin-associated protein ChIP-Seq data sets in mouse embryonic stem (ES) cells as well as genomic features to identify functional enhancer regions.

There is a growing awareness that histone modifications and chromatin organization influence pre-mRNA splicing.

However, how chromatin modifications and chromatin organization are reprogrammed upon fertilization in mammals has long remained elusive.

The epigenome encompasses a range of attributes including DNA methylation, histone modifications, and chromatin remodelers; together these components define the cellular transcriptome, identity, and function.

At the chromatin level, much research has focused on the role of histone modifications and chromatin remodeling complexes in promoting or preventing transcription [1], [2].