Additionally, the value of peptidomimetic modification and alterations based on posttranslational modifications for the design of APLs was examined.
Our research examined the relationship between NP surface modifications and alteration in mucus rheological properties.
Genomic global hypomethylation, gene promoter region hypermethylation, histone modifications, and alteration of miRNA patterns are major epigenetic changes in colorectal cancer.
It is not known whether a stepwise chain of epigenetic events occurs during hypoxia, ie changes in DNA methylation occurring before histone modifications and alteration in expression of downstream mi-RNAs.
Compared to the previous project, a number of modifications and alterations have been made.
The protocol, described in the materials and methods, was modified to increase the radiosynthetic reliability by iterative reaction parameter modifications and alterations to the purification strategies.
The present study was designed to investigate the potential oxidative protein modifications and alterations in proteasomal activity induced by DBAN in C6 glioma cells (C6 cells).
Every project we build interacts with the landscape and, once built, is an integral part of it: « architecture is a collection of modifications and alterations to the earth's surface for the purposes of satisfying human needs » (Morris 1880).
Besides the search and the managment of information, the approach can be used to validate the suitability of ontologies and their relevance to the particular application, suggesting modifications and alterations when appropriate.
The difficulty in standardization is in part due to the heterogeneous Tg immunoreactivity: differential splicing of Tg mRNA, various post-translational modifications, and alterations of biosynthesis regulation in thyroid tumor cells lead to exposure or masking of epitopes with resulting differences in Tg immunologic structure [23].
