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A better understanding of archaeal protein glycosylation provides insight into this post-translational modification across evolution as well as protein processing under extreme conditions.
Regardless of the means to search for interactions and the specific test used to evaluate the null hypothesis of no effect modification across genotypes, this framework incorporates the qualities of methods designed to efficiently alleviate the curse of dimensionality and correct for multiple comparisons with the specificity of interaction tests from regression.
In contrast, there was a slight decrease in SUMO-1 modification across all expression categories.
We further establish H4K5ac as a ubiquitous modification across the genome.
(A ) M data set for 1M7 modification across 188 single mutations along the GIR1 ribozyme sequence.
(A ) M data set for 1M7 modification across 127 single mutations along the class I ligase sequence.
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Furthermore, EBF1 binding to Gata3 regulatory sites induced repressive histone modifications across this region.
Here, we profile the dynamics of four histone modifications across seven tissue-resident macrophage populations.
Indeed, high-resolution mass spectrometry-based proteomic studies have identified thousands of acyl-protein modifications across hundreds of mitochondrial proteins.
We concurrently map relative levels of multiple histone modifications across multiple samples, each comprising as few as a thousand cells.
Here, we interrogated the transcriptome and several histone modifications across the genome during defined stages of cardiac differentiation.
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