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The cellular epigenome is dynamic in response to environmental signals, modifiable during normal cell differentiation and is heritable in daughter cells.
These cells represent a heterogeneous and poorly characterized population with modifiable self-renewal, proliferation and differentiation capabilities.
The ability to clone organisms by transferring a nucleus from a somatic cell into an enucleated egg cell, has led to the notion that heritable epigenetic processes, that are in principle modifiable, control gene expression in differentiation and aging.
A study using a polyacrylamide hydrogel modified with a vitronectin-derived HSPG-binding peptide recently demonstrated the first example of long-term self-renewal of hPSCs capable of in vitro differentiation into the three germ layers, cultured on protein low-fouling, peptide-presenting hydrogels with modifiable physical properties in defined medium [ 92].
* Is the situation modifiable?
And be modifiable.
Differentiation, tick.
There is technology differentiation.
Is Alzheimer's Disease Risk Modifiable?
The MTUP: modifiable temporal unit problem.
Health isn't immediately reparable; weight isn't immediately modifiable".
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