Moreover, we reflect on the implementation details of realizing such a modifiable architectural design.
In addition, surgical and patient specific factors (e.g., individual anatomy and comorbidities) are likely to play a role, though these are not modifiable by material design.
The two focussed interventions (Limpopo and Kampala), targeting modifiable determinants, are designed to be integrated into pre-existing health promotion curricula.
The co-twin control research design, comparing modifiable risk factors in twins discordant for CBP, offers a unique way to remove numerous confounding factors.
Hence, there is a need to identify modifiable risk factors to design appropriate preventive and therapeutic interventions during childhood and adolescence while there is still potential for BMD gain.
Cobalt chromium molybdenum (Co-Cr-Mo) materials are interesting for their excellent mechanical stability, corrosion resistance and possibility to be produced by additive manufacturing into complex designs with modifiable stiffness.
Prevention and treatment efforts designed to enhance modifiable factors such as gratitude, sense of purpose, and altruism may help promote resilience in highly trauma-exposed veterans.
We propose that the incorporation of these modifiable entities into the device design cycle could improve the device end product for better patient safety management.
Discovery of these determinants, especially modifiable ones, may enable the design of more effective programs for the prevention of CKD and ESRD.
Unfortunately, the maximum study size was not modifiable due to the naturalistic design of the study, which took place in a medical curriculum with pre-existing student cohorts.
