Sentence examples for modestly regulated from inspiring English sources

Cyclin D1 was only modestly regulated.

The plasma Lp(a) level is modestly regulated by life style modification and medication therapy, whereas it is significantly dependent on the isoform size of Apo(a), which is determined by the copy number of KIV-2 [ 16].

Although in metastatic cancer cells, JAGGED1 modestly regulated ZEB1, the miR-200c's target in invasion, studies in Drosophila revealed that only concurrent overexpression of Notch and Zfh1/ ZEB1 induced tumour metastases.

qPCR confirmed that AVEN is significantly downregulated in HT29 cells by vorinostat and LBH589 >5-fold at 24 h and only modestly regulated in HCT116 cells <2-fold at 24 h.

Another member of AP2 gene family (RAP2.2) binds to of PSY promoter and is shown to modestly regulate the transcript levels of PSY and PDS in Arabidopsis [ 28].

The mRNA targets whose levels decreased only modestly may be regulated primarily at the translation level or miRNAs may play only small modulatory roles in the expression of the proteins these mRNAs encode.

To comprehensively exclude false positives or targets that may be regulated only modestly, we directly analysed the impact of miRNA-1a-3p inhibition on the expression of all 53 target mRNAs in the DRG in vivo.

Knockdown of B-Myb in mES cells also decreases Oct4 RNA and protein abundance, while over-expression of B-MYB modestly up-regulates pou5f1 gene expression.

We show that the initial hypoxic response regulated by DosR contributes modestly to survival under hypoxic conditions in vitro but is dispensable for virulence in mice.

Other acetylation marks were not, or less significantly regulated by Myc: H4K16 was modestly induced in both groups of promoters (Fig. 2D), as well as at several other locations far from a TSS (data not shown).

The protein level of the major such pathway, CTR1, was modestly decreased by oxaliplatin treatment, yet was not regulated by DL-TBOA.