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In contrast, the expression of bone ECM-related genes such as type I collagen, osteonectin and Runx2 (Figure 4A) as well as osteocalcin and osteopontin (data not shown) was only modestly increased with the presence of implant disk.
HbAA levels modestly increased with increasing BSA in both females and males.
Hip bone loss in men was only modestly increased with ILI, a difference of ∼0.4% per year or 1.6% over 4 years in BMD.
In addition, BMI is only modestly increased with parity [ 50], and more substantial changes with BMI are associated with age [ 51].
Non-adherence to the national activity guideline also modestly increased with age (i.e. 53 % in 40 50 years, and 58%% in >70 years).
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However, GFAP staining of the corresponding brain region in Cln1/5 dko mice revealed a more profound astrocytosis, significantly greater than that seen in Cln5 ko mice and modestly increased compared with Cln1 ko mice, with the VPM/VPL and surrounding nuclei of Cln1/5 dko mice completely filled with hypertophic and intensely GFAP-immunoreactive astrocytes (Fig. 3A).
At this time point, the relative frequency of AMPKα1null OT1 T cells in the spleen was modestly increased compared with control cells (Fig. 2A).
21 Studies of macrolide use during pregnancy and IHPS report heterogeneous results but suggest a possible modestly increased risk with use in late pregnancy.
With the progression of hepatic steatosis to NASH and associated hepatic fibrosis, however, AST levels increase with a resultant rise in the AST ALT ratio. 1 11 γ glutamyltransferase (GGT) may also be modestly increased along with the NAFLD pattern for transaminases.
Multiple micronutrients were associated with modestly increased birth weight compared with folic acid, but, despite this weight gain, there was no significant reduction in early neonatal mortality.
The risk of mortality from coronary heart disease and stroke mortality is modestly increased in people with migraine, particularly those with aura.
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