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While numbers of mononuclear cells were significantly reduced (p = 0.011), neutrophils recovered from the BAL were only modestly attenuated (p = 0.052) in those animals.
HSV-2 0Δ104 was only modestly attenuated, and formed plaques 12-fold less efficiently in Vero cells treated with IFN-β relative to ICP0+ L7 cells (Fig. 2C).
HSV-2 0Δ104 was modestly attenuated, and grew to 100-fold lower titers in IFN-β-treated Vero cells relative to ICP0+ L7 cells (Fig. 3B).
HSV-2 0Δ104 was modestly attenuated, and thus mice inoculated with HSV-2 0Δ104 survived 4 days longer than mice inoculated with wild-type HSV-2 MS (i.e., duration of survival = 11±1 days p.i .. Nonetheless, only 1 of 25 mice survived ocular inoculation HSV-2 0Δ104 (Fig. 5D).
Adjustment for BMI modestly attenuated the associations.
The associations only modestly attenuated after full adjustment.
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We also tested IKKVII for its effect on the CD44+CD24− immunophenotype Additional file 4: Figure S3), and found that it modestly attenuates the CD44+CD24− population compared to GTCpFE.
In Table 1, we show that endometrial cancer risk is positively associated with time spent sitting (P for trend <0.01), as previously reported by Gierach et al. Adjustment for vigorous-intensity physical activity modestly attenuates RRs but sitting time still has a dose response relationship with endometrial cancer risk (P for trend <0.01).
While the PKC inhibitors routinely inhibited infection by at least 10-fold, RNAi modestly but significantly attenuated infection (∼2-fold).
This association was maintained when resting wall motion score was substituted for ejection fraction in the adjustment model (Model 5 adjusted HR 1.80, 95% CI 1.11 2.93), and attenuated modestly after further adjustment for inducible ischemia (Model 6 adjusted HR 1.61, 95% CI 0.95 2.78) (Table 4).
In the analysis of aPWV, we also adjusted for mean blood pressure at time of measurement to see whether the effect on aPWV was driven by the effect on mean blood pressure, and the effect was attenuated only modestly.
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