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In the heart, as in the brain, ischemic tolerance induced by preconditioning is associated with modest uncoupling of the mitochondrial respiratory chain [ 2, 3], which reduces the production of ROS by respiration.
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It has also been reported that low doses of uncoupler can increase ROS production in isolated myocytes [224], although how this might occur is unclear since in isolated mitochondria it is well established that even very modest uncoupling greatly decreases ROS production [242].
As noted above, even if there were modest uncoupling, this would be predicted to decrease ROS production rather than increase it.
That's what Harari means by the "uncoupling" of intelligence and consciousness.
He was in Argentina in 2001, when the uncoupling of the peso from the dollar sent the economy spinning.
In his book, Golden Kicks: The Shoes That Changed Sport, Jason Coles provides a correction to this uncoupling of sneakers from the stars who gave them life.
The figures suggest an uncoupling of morality from religion: you may be moral and religious, but the latter doesn't guarantee the former.
It turned out that when the train arrived in Belgrade for a one-hour stop, nobody was willing to authorize the uncoupling of those cars in Yugoslavia.
For the next three centuries, as Harrison observes, "the uncoupling of land from its natural role as the source of revenue for the state continued apace".
This uncoupling of predictors of AKI and mortality was unexpected and may warrant further investigation.
Uncoupling of SERCA by SLN increases ATP hydrolysis and heat production, and contributes to temperature homeostasis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com