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In 1968, The Lancet published the results of a modest trial of what is now regarded as among the most important medical advances of the twentieth century.
With the modest trial selection parameters chosen here, almost all patients who tolerated full-course treatment had preserved weight and performance status, and controlled pain over the study period (not shown).
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Places lets them signal where they are to their friends on the network, in much the same way that they can "tag" themselves in photos.Several advertisers have already run modest trials on location-based social networks.
Analyses of time to progression or response rate surrogate endpoints, measures that do not include a survival in the surrogate, report more modest trial-level associations.
If six months doesn't sound like a lot, consider the economic incentive here: for the price of a modest clinical trial in children (costing at most $3 million), Schering can extend the life of its basic patent half a year and earn close to $1billion.
However, a 10-year follow-up identified modest post-trial risk reductions [ 42], again suggesting a delayed benefit.
However, there was also a modest reduction in trial-to-trial failure rates after SWE-induced plasticity if compared with the undeprived control, and this was also found to be stimulus intensity-dependent (Fig. 5A and B).
As expected based on previous studies, 5, 14 the collective hand paths of the total participants were relatively straight, with small corrective movements and modest amounts of trial-to-trial variability (see Figures 6 and 7).
Usually, information is fragmented across many small or modest-sized trials, with selective publication and reporting.
The present meta-regression analysis aims to shed light on this specific point, by increasing statistical power and enhancing the precision of estimates across multiple modest-size trials.
The response rate was more modest in this trial, being 6.2%.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com