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Although the inhibition of CD40 signaling by HOIPΔRBR was modest, the level of inhibition was consistent with the modest level of IPTG-induced HOIPΔRBR expression (slightly greater than that of endogenous HOIP; Fig. 4a).
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While the moves on the day are fairly modest, the levels being reached are key.
Minimizing the risk, he said, the company's shares have been trading at earnings multiples more modest than the level of 50 or more common for technology companies.
But the study also tracked the health outcomes of each group, and there the results were more surprising: With a few modest exceptions, the level of insurance had no significant effect on the participants' actual wellness.
"To have a modest uptick in the level of disclosure is not much of an improvement".
There was a modest increase in the level of aging in RTFO-aged binders due to the addition of RAS.
Exports to the United States rose a modest 7.2 percent from the level of a year ago, well off the 25 percent growth pace in April.
Annan's April 12 ceasefire has led to only modest reductions in the level of daily carnage, with both sides accusing each other of multiple breaches of the truce.
Thus, it is evident that a modest decrease in the level of SF2/ASF can augment the level of JCV replication in the permissive cells.
miRNA binding to a target usually has only a modest effect on the level of the target mRNA and a greater effect on the encoded protein.
This suggestion of an effect of Neurl4 on microtubules is supported by the modest reduction in the level of γ-tubulin in centrosomes in Neurl4 mutant embryos.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com