Worster and colleagues also reported no difference between B type natriuretic peptide and NTproBNP, with similarly high diagnostic sensitivity and modest specificity.
The two-item Whooley questions have high sensitivity and modest specificity in the detection of depression.
While the QVSS has demonstrated good sensitivity and modest specificity compared with stroke status determined by a neurologist in a general medicine population (25), its performance in a population of people with diabetes has not been evaluated.
The original validation study reported that the two-item version of the questions had high sensitivity (0.95, 95% CI 0.89 to 0.98) and modest specificity (0.56, 95% CI 0.52 to 0.61).
Assessment of CAD with coronary computed tomography angiography (CCTA) is safe, cost-effective, and accurate, albeit with a modest specificity.
1 However, only a small portion of influenza cases are clinically diagnosed as influenza or ILI and ILI only has a modest specificity in predicting an influenza infection.
The results show that the ligands bind with high affinity and stabilize KRAS22-RT G4 with modest specificity over duplex DNA.
The resulting peptides bound to KSBcl-2 and BHRF1 in preference to Bfl-1, Bcl-w, Bcl-xL, and Bcl-2 but showed only modest specificity over Mcl-1.
B3 was chosen because it had the highest frequency of recovery, and A12 was chosen based on the presence of I2dM, an untested substitution, and E2gG, which was shown to provide modest specificity against Bcl-w in previously published Bim substitution SPOT arrays (Supplementary Table 1).
