Suggestions(5)
Exact(7)
Despite a modest sequence identity, the two TRFH domains have the same entirely α-helical architecture, resembling a twisted horseshoe.
Moreover, the hpr, gck and sga genes inferred from the genomic context display only modest sequence identity with Methylobacterium prototypes (Fig. 4), further suggesting that the serine cycle in S. pomeroyi belongs to an independent evolutionary lineage.
Although the accuracy of the detailed hIL-3 receptor α-chain structure may be limited by the modest sequence identity, the overall arrangement of its two domains in the final complex can be assigned with high confidence, so the role of the receptor α-chain in the assembly of the dodecamer complex can be assessed with reasonable certainty (see below).
However, matching of specific isoforms to those of mammalian subunit IV (5A with IV-1/IV-2 and 5B with IV-2/IV-1) is not possible based on the modest sequence identity of ~20% for each combination [ 3].
It remains to be investigated if additional substrates are taken up by the MFS permease including possible substrates for the upregulated GH42, which exhibits modest sequence identity (≈30%) to characterized GH42 enzymes.
Each aef operon encodes 4 6 proteins and has modest sequence identity to products of corresponding haf genes (38%57%%) and to F17 fimbrial adhesins (25%64%%) produced by pathogenic Escherichia coli associated with septicemic diarrheal diseases.
Similar(53)
Both ERα and ERβ share a modest overall sequence identity (47%) [ 3].
Similar structures, albeit with very modest levels of sequence identity, have also been found associated with voltage-regulated phosphatases (14% identical to NaChBac)(47) and voltage-activated proton channels (12% identical to NaChBac).
A major gene (Gp-9), identified as a putative pheromone-binding protein on the basis of a modest amino acid sequence identity, has been suggested to influence the expression of colony social organization.
Despite the relatively modest level of sequence identity, a reasonable alignment could be made.
We conclude that there is a modest effect of sequence identity within the enhancer DNA segments that are contacted by the helix-B region of Hin.
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