Exact(5)
But in almost all cases they carry only a modest risk for the disease.
What they didn't say: The 3 Series represents a major test and a modest risk for BMW, with a new turbocharged 4-cylinder engine replacing the venerable in-line 6 in the basic 328i model.
Polygenic models in which the existence of a large number of breast cancer susceptibility genes, each one conferring modest risk for developing the disease have been also proposed.
Obesity has been associated with a modest risk for developing RA, but the rapid increase in obesity prevalence may be responsible for much of the increase in RA incidence [ 34].
Children who appear to have recovered by age 4 from early delay are at modest risk for continuing difficulties, but this appears to be no higher than the risk for other 4-year-olds with equivalent scores, reflecting the continuing variability in longitudinal outcome after age 4. All children in the low normal range at age 4 merit continuing monitoring.
Similar(55)
Individual immune responses are important in determining the path of an infection, and a limited number of other non-viral determinants with modest risks for HPV infection and progression have been well established [ 6– 11].
All published obesity loci detected by GWA confer a modest to small risk for obesity.
NBN p.Arg215Trp was of interest because association studies have found evidence that it confers modest risk of several cancers (for review, see [ 66]), and there is biochemical evidence, albeit somewhat conflicting, of altered function of this nibrin allele [ 67, 68].
Even for patients at modest risk of heart attacks meaning that they have heart disease, diabetes, or a combination of some risk factors the new guidelines suggest lowering cholesterol at least 30-40%.
The prudent pattern was associated with a modest risk reduction for type 2 diabetes (multivariate relative risk for highest vs lowest quintiles, 0.84; 95% CI: 0.70 1.00) whereas the higher western-pattern scores were associated with a considerable increased risk for type 2 diabetes (relative risk, 1.59; 95% CI: 1.32 1.93; p < 0.001).
Although recent studies have shown that heredity is a dominant factor in lumbar disc degeneration, heavy lifting and awkward working positions as well as obesity and joint injury may be modest risk factors for disc degeneration, and also for arthrosis of the knee and hip [ 18, 19].
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