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The lung and stomach wall showed modest retention.
However, in MMU2 and LCC9 cells, tamoxifen caused only a modest retention in G1 and inhibition of progression into S-phase, which was not significant.
The fluorescent labels contribute to the retention of glycans on PGC: PA, which is a label with only modest retention in PGC, results in superb PGC separations of labeled glycans, whereas derivatization with a label such as 2-AB, which has pronounced influence on glycan retention on PGC, results in inferior resolution [ 174].
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Antibody fragments have shown targeted specificity to their antigens, but only modest tissue retention times in vivo and in vitro.
Genetic deletion of nephron ETA causes very modest fluid retention that does not alter arterial pressure.
Taken together, these data suggest that nephron ETA KO causes modest fluid retention that is evident when Na intake is high.
A recent phase IIA trial in patients with diabetic nephropathy using atrasentan in doses that caused only modest fluid retention showed significant reductions in albuminuria over an 8-week period [ 17]; further trials are planned to determine whether ETA blockade slows progression of diabetic kidney disease.
However, IONP delivery is restricted by its modest leakage and retention in tumors.
Carbamylation resulted in a modest shift in retention times of peptides because the ionizable amine groups are converted to more hydrophobic amide functionalities.
With either column there is a modest increase in retention of standard WAGGDASGK over the range pH 3 5 as its carboxyl functional groups ionize.
The presence of MLG interlayer significantly improved the Li-capacity and coulombic efficiency in each cycle, even though the improvement in capacity retention was modest.
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