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Fig. 1 shows that these cell lines exhibited the differential TRAIL sensitivity; MDA-231, DOV13, OV433 and OVCA420 cells were sensitive to TRAIL whereas the rest of lines were resistant to TRAIL except MCF-7 cells that showed modest resistance.
Putting up a modest resistance, the State Department proposed a cap of fifty thousand.
Compared with C57BL/6 mice, BALB/c mice exhibited modest resistance to infection after deposition of 104 CFU/lung.
We show that, although transcriptional regulation provides only modest resistance relative to fork stabilization, it contributes significantly to cell survival.
In the rad3Δ background, mrc1 expression provides modest resistance to HU, and it is required for all of the cdc10-2E-dependent resistance to MMS (Figure 4A,C).
In the rad3Δ background, which lacks any cell-cycle arrest, constitutive expression of mik1 provides modest resistance to both treatments, accounting for about half of the resistance due to cdc10-2E-dependent G1/S transcript expression (Figure 4B,C).
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They are hardenable by heat treatment, have modest corrosion resistance, and are employed in cutlery, surgical instruments, wrenches, and turbines.
While modest insulin resistance is physiological in pregnancy and generates maternal glucose, free fatty acids and amino acids as substrates for fetal growth, obese pregnant women are more insulin resistant than their lean counterparts 6 leading to a further amplification of nutrient availability with consequent excessive fetal growth.
A collateral sensitivity or a very modest cross-resistance to BBR 3464 was found in 2 ovarian cancer cell lines with experimentally induced resistance to cisplatin.
Moreover, in this nonrecessive case, the addition of an open refuge may not be very helpful, producing mere modest delays in resistance development as shown in Fig. 1D, or even actually accelerating resistance evolution (Mohammed-Awel et al. 2007).
Restoration of extended MBF-dependent transcription provides modest, but reproducible, resistance to HU in both rad3Δ and cds1Δ cells, comparable in degree to the resistance provided by the cell-cycle arrest function of the checkpoint.
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