Sentence examples for modest prolongation of from inspiring English sources
Although docetaxel is the standard of care for these patients and is associated with a modest prolongation of survival, there is an urgent need for novel treatment strategies for metastatic prostate cancer.
Conclusions This study confirmed a modest prolongation of QT interval with citalopram, and identified additional antidepressants with similar observed risk.
RCCTs have contributed to improved adjuvant therapy and to modest prolongation of survival in the advanced disease setting for many malignancies.
A modest prolongation of time to next therapy but not of OS was observed (23); a general recommendation for PLD use as maintenance therapy cannot be given (24).
In spite of the efficacy of adjuvant carmustine/lomustine-based chemoradiotherapy (RT) in achieving modest prolongation of median survival, the survival benefit did not exceed a few months.
At the gemcitabine dose of 120 μg/gm (~ 2.4 mg/mouse), used in previous reports [ 26] weekly for 3 doses, there was modest prolongation of median survival, with 0/5 and 2/6 long-term survivors in the two experiments.
48 When tumors truly become castrate-resistant, patients are offered docetaxel-based cytotoxic chemotherapy, which results in significant palliation of symptoms but only a modest prolongation in survival.
Intraperitoneal administration of IL-2 resulted in an approximately 25% overall response rate in two studies [53], [54], while IL-2 in combination with retinoic acid as a maintenance therapy demonstrated a relatively modest, but statistically significant, prolongation of progression-free and overall survival in a phase II trial [55], [56].
Once again, the benefits were relatively modest in terms of prolongation of median overall survival, but a minority of patients achieved what appeared to be more durable responses.
Although these inhibitors were studied mainly in solid tumors, with modest responses reported and prolongation of stable disease at best, they have yet to be studied in CTCL.
Patients receiving rivaroxaban may have mild to moderate prolongation of clotting time tests beyond reference range, however the degree of prolongation is variable among patients.
