Sentence examples for modest potency from inspiring English sources

In general, modest potency enhancements were observed.

Biological evaluation revealed the constrained analog to be a selective serotonin 2C agonist with modest potency.

These bicyclic systems block the NR SRC interaction with modest potency.

The compounds exhibited modest potency on TF/VIIa with selectivity over Factor Xa and thrombin.

One of the antibodies did inhibit virus infection, albeit with modest potency.

The mAbs, including a whole IgG 8K8 molecule, neutralized primary HIV-1 of clades B and C in a pseudotyped virus assay with comparable, albeit relatively modest potency.

Analogues 6 and 7 bearing secondary alkyl or cycloalkyl groups showed low potency at the target enzyme, coupled with modest levels (LE ⩽ 0.30) of ligand efficiency.

Both the phenyl- and benzylphosphonamidates (1a and 1b) exhibited only modest inhibitory potency against.

Because of modest cellular potency of compound 2 (68% inhibition at 2 µM), a small modification of the hydantoin substituent was attempted to improve the cellular potency while maintaining the inhibitory activity.

The antifungal activity was labile to modification of the enol ether functionality and almost all of the modified compounds lacked the activity except for the analogue with an introduction of a methylthio group at the C-6 position, which retained a modest antifungal potency against Cryptococcus neoformans.

Although the former test showed modest mutagenic potency, the latter was quite revealing.