The modest significance value reflects the small overall effect on AO in the HD population, and this is due to the low frequency of the deletion (0.25%) and duplication alleles (1.9%).
A recent meta-analysis of 30 trials of nurse-delivered cessation advice found a modest overall positive effect when compared with controls or usual care (OR 1.47, 95%CI: 1.29 1.68) [ 17].
However, the overall effect is modest.
Previous studies that focused on the effect of immigrants on the achievement of native students have found modest negative effects or no overall effect.
The overall effect is modest compared to the more generic health state descriptions such as the EQ-5D.
The results demonstrate that menopausal symptoms are perceived by patients to have a significant impact on utility, but the overall effect is modest compared to the more generic health state descriptions such as the EQ-5D.
However, it has also been shown that while treatment effects are modest overall regardless of initial therapy, some nonresponders to one treatment may still be responsive to an alternative medication.
The overall effect is a modest variation of soot volume fraction if radiation is included.
Overall effect sizes were modest but, compared with the findings on BP, those for a measure of mean HbA1c collected over a time period of up to 20 years prior to cognitive testing and for lifetime smoking history appeared to be more robust across the total sample.
