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Impressive changes in gene expression were found in β cells exposed to either very modest or severe hyperglycemia.
16, 18 The usual recommended daily dose of sitagliptin is 100 mg; however, because renal insufficiency increases drug exposure, the dose should be reduced in individuals with modest or severe renal dysfunction.
Similar(58)
Is it mild or severe?
The pain can be mild or severe.
Was it mild, moderate or severe?
Any sudden or severe pain.
Constant back pain or severe asthma?
Its intensity was very severe or severe.
Moderate or severe intensity D.
Moderate or severe pain intensity d.
To make less harsh or severe; moderate.
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