Sentence examples for modest modifications of from inspiring English sources

The methods can be implemented with only modest modifications of current large-scale sequencing pipelines and are highly synergistic with the next generation of sequencing technologies.

PEG-mediated transformation was reported to be ineffective [but later shown to require only modest modifications of the existing protocol (Oelgeschläger and Rother 2009)], but cationic liposomes could be used to transform Methanosarcina species (Metcalf et al. 1997).

A systematic analysis of these parameters determined for loop-deletion OccK1 mutants enabled the identification of significant changes of the differential activation enthalpies and entropies but modest modifications of the differential transition free energies.

Modest modifications of facility records and registers (as needed) to remind providers to implement and record best practices and to permit monthly calculation of quality of care indicators by facility teams (e.g. local rubber stamp to imprint AMTSL/ENC check-off boxes in partogram; insertion of columns in registers to track postpartum vital signs of mother and newborn).

Therefore, implementation of MC MDT requires only a modest modification of conventional HMM-based recognizers.

Yet if cars were not used for daily purposes in Macao, these road links would nevertheless be adequate to get cars in and out of Macao, with modest modification of the road network in peninsular Macao.

We also observed modest modification of FLIP and caspase-8.

19 However, it is not clear whether increasing numbers of new drugs are indicative of radical new breakthroughs or more modest, relatively minor modifications of existing marketed drugs.

These compounds contained modest modifications to the C ring of the scaffold but retained hydroxyl substitutions in the A and B rings.

Unfortunately, despite the widespread publication of recommendations over the last decade and some modest modifications in the pattern of antibiotic utilization (61), the willingness of French general practitioners to change their antibiotic-prescribing habits has been at best grudging and at worst nonexistent (29, 67).

IT might seem only a modest modification to a Web site.