Sentence examples for modest linkage from inspiring English sources

There is strong evidence linking PSE to parental competence, and more modest linkage to parental psychological functioning.

18 There is only modest linkage disequilibrium between that SNP and the SNP tested in our study (r 2=0.5).

In all samples, a modest linkage disequilibrium was observed between rs2234693 and rs9340799 (D' = 0.479, r = 0.089).

It is clear that the signals of association are not restricted to regions of peak linkage, but are in fact in regions with modest linkage.

These SNPs are in modest linkage disequilibrium (r=0.57) and were also moderately associated with lower facial depth (both P<9.9×10-4).

Pairwise linkage disequilibrium indicated that these 10 SNPs were in modest linkage disequilibrium and formed 3 haplotype blocks in this region.

While genome wide association studies are appropriately powered to detect common variants of modest effect, linkage studies are more effective in detecting rare variants of larger effect even in the presence of allelic heterogeneity.

Finally, in an attempt to map the genes that predispose to the common causes of ESRD, a genome-wide scan in 1,023 individuals with CKD from 483 black families was performed by Freedman et al. 72 Their results showed a modest evidence of linkage to 13q33.3 near D13S796 on multipoint, nonparametric linkage analysis (LOD = 1.72).

54 This provides a strong rationale for investigating the KIR gene cluster as a candidate susceptibility locus in multiple sclerosis subsequent to our finding of association with HLA- C. The fact that the KIR gene cluster lies on chromosome 19 where modest evidence of linkage was observed in the recent high-density screen for linkage in multiple sclerosis 24 lends further support.

On the basis of the "modest" value for linkage and multiple phenotypes under consideration, some of the regions detected with suggestive linkage in either study may also correspond to false positive results.

A meta-analysis of the results of five GWLS yielded modest evidence for linkage at several loci, but cautioned that insufficient data were available for conclusive results.