Sentence examples for modest life span from inspiring English sources
The fund should have only one purpose, charity, and a modest life span.
Consistent with this, mice with partial inactivation of p110α have a modest life span extension.
Because of their modest life span and aging-associated pathologies that parallel humans, including arthritis [ 4], marmosets have also shown great promise as a non-human primate model of aging and aging-related disease [ 5].
This correlated with a modest median life span extension of approximately 6% in the male p110αD933A/WT mice that survived to middle age.
It has only a modest effect on life span, but it causes costly chronic illnesses, like diabetes.
This beneficial effect of p110α inactivation on metabolism correlates with a modest extension in life span.
Importantly, when Zmpste24-null mice were fed with sodium butyrate, a modest extension of life span and amelioration of premature aging phenotypes was observed, suggesting that HDAC inhibition might have a therapeutic potential.
Our data show that a triple knockout has no effect on females but has a modest effect on male life span, in addition to almost complete male sterility.
Through a detailed series of studies in which we examine the effects of expression of dSir2 at low, moderate and high levels on life span, we demonstrate that modest levels of dSir2 are indeed effective at extending life span, and that high levels of expression likely induce a cellular stress response that is reflected by induction of dnaJ-H.
Although the degree of thrombocytopaenia in the splenectomised BCL-2tg animals is modest, when the increase in platelet life span in these animals is taken into account, it indicates a significant residual defect, which is amplified under conditions of emergency thrombopoiesis.
"The very big changes you see from early adolescence to early adulthood are greatly muted after 30, 35," personality psychologist Paul T. Costa told New York magazine's Science of Us. "There are still changes in personality after that, but they're very, very modest compared to earlier phases in the life span".
