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Although miR modulation was quite modest, it showed reproducibility among all donors tested (n = 12) and results were statistically significant with respect to untreated controls.
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Moreover, it showed modest difference of the risk of lung and UADT cancers between cigarette smokers and nonsmokers both in single SNP analyses and in combined double SNP analyses.
It showed modest inhibition of microtubule assembly; the opposite of that from paclitaxel! Howarth et al. synthesized protected 17a– 17d based on the hypothesis that paclitaxel behaves as a GTP mimic, with the baccatin III core acting as the guanosine part of GTP and the side chain representing a triphosphate.
The three-year-old pilot project was ended in March after it showed only modest results.
Later, TM was tested in numerous human cancer trials, where it showed only modest effects.
When the Elwood trial ended in 1973, it showed a modest but not statistically significant reduction in heart attacks among the group taking aspirin.
It showed excellent reliability and modest correlation with 4 commonly used microscopic assessment systems.
The confirmatory form of the probabilistic argument is more modest; it aims to show that there is a considerable contribution to the argument for M arising from the facts indicated.
As regards pazopanib, it shows modest activity as single agent; however, it has been found to synergise with docetaxel in docetaxel-resistant BC cells.
Indeed, the Bush era is a perfect example of why liberals shouldn't be freaked out by the Tea Party's modest gains right now, because it shows how quickly and easily temporary limits on domestic spending can disappear, and why the creation of a new entitlement often looms larger than the outcome of short term budget battles.
Lichter calls the response "modest," but significant in that it shows that antibody therapies, considered best for blood cancers, can work against solid tumors too.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com