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Indeed, regulation of these 'local' renin-angiotensin systems has received modest investigation.
Apart from hemodynamic studies, most histopathological analyses are confined to a modest investigation with poor identification of engrafting cell elements and their effective viability and activity in the regenerated tissue.
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As the modest investigations in this clever series tend to do, this one dovetails with historic events — here the politically charged feud between the Russian brass and the Polish government in exile over the massacre of 22,000 Polish officers in the Katyn forest.
Although the sample size was quite small, that investigation provides a modest degree of corroboration of our findings.
The proposal was modest, urging more investigation before charges are filed; nonetheless, when fundamentalists objected, it was discarded.
It's a modest yet intricate investigation into architectural density and space.
The SNP associations identified in this study, although modest, merit further investigation in a larger cohort of suicide attempters and may contribute to future meta-analysis of suicidal behaviour susceptibility loci.
Sixth, the sample size was modest for the investigation of therapist effects and larger samples may be more sensitive in detecting therapist variables that are associated with good outcome.
Vinflunine remains the only agent to demonstrate an improvement in OS in the second-line treatment of UC and should be accepted as the standard of care with the recognition that the median 2-month survival benefit is modest, and the investigation of novel agents that target driver pathways is imperative.
However, the effects of T cell peptide therapy on allergen-induced mast cell degranulation and acute allergic inflammation observed in clinical trials are modest and deserve further investigation [ 44].
Also warranting further investigation, although modest and awaiting post hoc statistical analysis, are the differences between the two active treatments in effect sizes observed in some CHIP-CE PRF and WFIRS-P domains, whiCHIP-CE PRF implicandons for individualized treatment [ 10].
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