Sentence examples for modest inhibitory effect from inspiring English sources

In this study, we showed that single-agent therapy with either AZD6244 or MK2206 has a modest inhibitory effect on lung cancer cell lines.

The results showed that this oligonucleotide clearly inhibited translation from AUG1 (≈30%) while having only a very modest inhibitory effect on translation from AUG2 (Figure S2).

Although the western blot data confirm a marked increase in p42- and p44 ERK phosphorylation following a poly-l-arginine challenge, the selective inhibitor, PD 98059, only produced a modest inhibitory effect on IL-8 secretion.

Attempts to counteract the inhibitory effect of DFMO by addition of either 100 µM putrescine (Figure 2C) or 100 µM spermidine (Figure 2D) had no effect, and spermidine alone actually had a modest inhibitory effect at 24 h.

Overexpression of AtICS1 in roots had a modest inhibitory effect (FI = 67, P = 0.002).

In contrast, EGF-RKT antagonism had only a modest inhibitory effect on MMP-1 production.

The modest inhibitory effects of H1N1 and H5N1 infection on ifnar2 gene expression were not statistically significant.

Although this showed modest inhibitory effects of peroxide on P402-OH/P564-OH, strikingreaterater inhibition of N803-OH was revealed (Fig 1A supplementary Fig S1A online).

Modest inhibitory effects were observed with concentrations as low as 5 nM, with optimal inhibition of aggregation observed at 500 nM, when aggregation was reduced by 22±4%4% (n = 5).

Quantification of angiogenesis revealed modest inhibitory effects of 2-MeOE2 (20 and 43% at 1 and 10 mg kg−1 respectively; NS) but a significant (83%, P<0.05) reduction at the highest dose tested.

In view of these findings and the modest inhibitory effects of MBP on testosterone production by rat testis explants, we concluded that it is not possible to reproduce the in vivo effects of DBP/MBP on steroidogenesis using fetal testis explants in vitro.