Exact(16)
Immunohistochemical characterization showed that the in vivo MPEG-b- PCL-ran-PfLA) diblock copolyMPEG-b- PCL-ran-PfLAly a MPEG-b- PCL-ran-PfLAresponse.
At week 6, compared with SED groups, the TRE groups manifested modest inflammatory cells with pro-inflammatory cytokines (i.e., TNF-α and IL-6), improved collagen alignment and higher glycosaminoglycan (GAG) content, particularly in the PGI-TRE group.
This contrasted with a modest inflammatory response seen in the NMA regimen in which intestinal damage was limited.
VEGF-C staining at the peripheral margins of the grafts was associated with a modest inflammatory infiltrate into the skin graft.
In summary, pathway analysis of inflammation-associated genes is a powerful approach for determining genetic risk factors for both inflammatory diseases and other diseases that may have an under-appreciated modest inflammatory component, such as cancers.
The close relationship between intestinal damage and inflammation was further underscored by the fact that NMA resulted in only a modest inflammatory response with a completely different time course, and the virtual absence of severe intestinal damage.
Similar(44)
Of note, saline-treated mice showed a modest increase in this enzyme, suggesting that the instillation procedure can induce a minor inflammatory response within the lungs.
Patients after cardiac arrest have a modest systemic inflammatory response compared to healthy controls.
There was a modest chronic inflammatory exudate composed mainly of lymphocytes, monocytes, a few plasma cells, and occasionally a few polymorphonuclear leukocytes.
Subsequent histological analysis of the joints showed a normal synovial membrane with only occasional modest cellular inflammatory infiltration but no pannus formation or cartilage and bone erosion (data not shown).
In turn, VILI induces a more modest acute inflammatory response with mild lung neutrophil accumulation and distinct mechanisms leading to inflammation and barrier dysfunction involving a different set of signaling molecules [ 23, 45- 47] and transcription factors [ 48].
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