Sentence examples for modest in vitro from inspiring English sources

Didemnidine B (167) showed modest in vitro growth inhibition against P. falciparum (IC50 8.4 µM and T. brucei rhodesiense (9.9 µM).

Although the enhancement of gemcitabine toxicity following GSK-3 inhibition appears to be modest in vitro, we recognize that this does not exclude the potential for positive drug interaction in vivo, and this remains to be tested.

Its modest in vitro potency (IC50 around 1 μM) was offset by good pharmacokinetic properties giving 100% cure in a mouse model of stage 2 disease following a 25 mg/kg once a day for 7 days oral dosing.

New peptide pGlu Asn Trp (pENW), initially extracted from snake venom, significantly attenuates the formation of arterial and venous thrombi in vivo, and has modest in-vitro antiplatelet activity.

It appeared from these data that pazopanib demonstrated modest selectivity in vitro.

Although the increased toxicity for drug-loaded nanoparticles is modest, these in vitro studies do not include a mechanism to clear the drug.

This compound exhibited a modest MIC in vitro against strains from nine different BCC species, including multi-drug resistant clinical isolates (MIC = 8-64 μg/ml), and a weak MIC (128 μg/ml) against A baumannii.

SNP rs11872992 had a modest functional effect in vitro.

However, some rpoB mutations are associated with only a modest decrease in in vitro fitness [ 17].

This indicates that the slower diffusion of DNA-bound transposase than of free transposase has only modest impact for in vitro experiments.

Some inhibitors of the PI3K/Akt pathway are currently used in clinical trials as anticancer agents, however, when used against breast cancers (BCs), they show modest effects either in vitro or in vivo.