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Although the sample size was relatively modest in this study, we were able to address the study aims.
First, the overall adjusted R values are quite modest in this study and in other studies, which suggests that there is considerable variability in the behavioral response to the cost of housing.
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The modest LD in this study, rarely extending beyond 5 kb, confirms that genome-wide allelic association studies will require a very dense set of markers covering all genes.
Despite the modest power in this study, all of the four STAT4 SNPs were associated with JIA, with the strongest association for rs8179673 (allelic OR=1.25, 95% CI 1.11 to 1.4, trend p=0.0002) (table 2).
Although the contribution of Gαs to odor responses was very modest in the study by Yao and Carlson [30], observable effects were reported.
"Evidence that we are not as likely to recognize and encourage talent (even modest talent, as in this study) shakes our confidence and (I hope) will make us more attentive to our limitations in recognizing talent where we don't expect to find it".
First, the modest sample size in this study could impede our discovery of less-strong associations; larger sample size is required to determine whether the insignificant results were false negative.
PEEP was applied for a short time (2 days only); the effects of long-term PEEP for more than 2 days, even at the modest level employed in this study, are unknown.
Potential explanations for the lack of response include insufficient power to detect modest improvements in this small study and mechanisms that may be specific to blockade of IL-17RA.
37 The good news of a modest decline in hypercholesterolaemia in this study concurs with findings for the developed world.
The modest sample size available in this study necessitates a circumspect view of the data, particularly with regard to the tests of moderation and mediation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com