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The effects of PGH thus appear (at best) modest in normal human pregnancy.
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We show that NF1 is expressed at modest levels in normal LCLs and fluctuates following serum deprivation (Additional file 10), suggesting that EBV transformation of B lymphocytes did not abrogate baseline or serum-dependent NF1 expression.
This would be along the lines of a proposal by Harvard professors David S. Scharfstein and Adi Sunderam (though they would have the government offer insurance on a modest share of mortgages even in normal times, to maintain the capacity to scale up when needed).
Modest SERCA2 expression was detected in normal cervix tissues (n=9) and cancer adjacent normal cervix tissue (NAT, n=14).
Modest stromal staining was observed in normal mammary tissue indicating the presence of nitrotyrosine residues (Fig. 12A).
In normal cells, modest reactive oxygen species (ROS) modulates many cellular processes through stress-kinase pathways, including mitogen-activated protein kinase (MAPK) pathway.
At its 41st meeting in 1993, the JECFA recognized that the model on which the PTWI for Cd was based did not include a safety factor, and thus the PTWI for Cd has a very modest safety margin between exposure in normal diet and exposure that produces adverse effects (WHO 1993).
These studies have demonstrated that the rates of synthesis and clearance are similar in normal subjects; thus, modest perturbations can result in accumulation of Aβ in the brain [ 9].
Its lack of toxicity as a single agent in vitro and in vivo as well as its limited ability to induce apoptosis in normal cells at modest TRAIL concentrations bode well for its potential therapeutic utility.
A modest increase in ECAR was also observed in normal B cells.
On the other hand, ISG15 expression was modest in brain tissue obtained from normal individuals (lane 1 and 2).
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