Sentence examples for modest immune response from inspiring English sources

Only a modest immune response was seen, with micro-neutralization antibodies being developed at 12 times the dose used in the seasonal influenza vaccine.

One reason for the modest immune response can be that the concentrations of antibodies against Hib were relatively high even before vaccination, in both previously vaccinated and unvaccinated patients, probably due to the circulation of Hib in our population and the lack of compulsory Hib vaccination before 2007 in the Polish immunization schedule.

This is a particular problem with oral delivery; where high doses of antigen are required to generate even modest immune responses.

Prof Helen McShane, from the University of Oxford, who developed the vaccine, said: "[It] induced modest immune responses against TB in the infants, but these were much lower than those previously seen in adults, and were insufficient to protect against the disease.

Thus, whereas the higher doses antigen of Ag85B-TB10.4 (5 and 15 µg) in IC31®, induced very modest immune responses that did not protect against M.tb challenge, reducing the dose to 0.5 µg Ag85B-TB10.4 IC31®31® led to a selective increase in the numbers of polyfunctional T cells, which in turn increased the protection against M.tb to the same level as BCG.

Furthermore, although only a modest mucosal immune response was observed with LP-E7, this strain was able to induce a significant regression of HPV-induced tumors in contrast to LL-E7.

However, we observe a modest adaptive immune response that abrogates the efficacy of additional rAAV2 administration.

To partially induce innate immune responses in Adar1; p53 MEFs, we transfected these cells with levels of an in-vitro-transcribed Fluc mRNA that has been shown previously to induce a modest innate immune response in HeLa cells (Vitali and Scadden, 2010).

This modest reduction in immune response to the vector might reflect increased attenuation of the rNDVs associated with the insertion of the HA gene, as indicated above by the MDT assay, or might reflect an effect on expression of the NDV HN protein (the antigen-specificity of the antibodies measured by the HI assay) due to the presence of the upstream foreign gene, or both.

Only a modest increase in the immune response was observed when plain rHBV was administered intratracheally at the same dose.

In one randomized controlled study of TIV (Flulaval™) in children 6 35 months, seroprotection rates in the full-dose group were 63.6 92.4%, and in the half-dose group were 53.4 84.7%, yet despite a modest increase in immune responses with the full- vs. half-dose, the GMTs were not significantly different.