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We observed a modest excess of eQTL for which the major allele was associated with lower gene expression levels (56%, binomial test p = 1.15 × 10−7).
Although platinum-based 'standard' combination chemotherapy regimens have widely been used and reported to be generally safe, results of randomised trials reported nonsignificant but modest excess of post-surgical morbidity and mortality (Depierre et al, 2002; Pisters et al, 2007).
In the patients diagnosed with diabetes at ages 30 49 years, the modest excess of pancreatic cancer deaths did not reflect raised risk at any particular point in follow-up.
Compared to the WT serosa, the Tc-zen1 RNAi posterior amniotic fold comprises a modest excess of EE tissue beyond that which directly covers the yolk (compare Fig. 1B,C and Fig. 1J,K).
7 The only suggestion of an adverse health effect was a modest excess of lung cancer deaths (13 observed, 10.5 expected deaths) which was concentrated in the period of follow-up 15 years or more after first exposure (8 observed, 3.8 expected deaths).
The modest excess of all-cause absences (relative excess of 8.4%%) observed during influenza epidemic periods may be due to the more frequent and prolonged epidemics in subtropical HK [ 17] compared to temperate locations which typically only experience influenza epidemics in the winter, thus spreading the impact out over a longer period.
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One of these is a North American multicenter investigation, discussed in our commentary, which reported modest "excesses of brain cancer" and "cancer of connective and soft tissue" (Mundt et al. 2000).
However, as male breast cancers are rare, the modest excess risk of second prostate cancer may amount to equally many excess cases as second breast cancer.
There is an excess of spring births, albeit a numerically modest excess, among people with MS with the implication that pregnancy-associated factors may be relevant to the risk of MS. There is also some evidence of season of birth effects in HD with a slight excess of spring births in young people with HD[ 23].
The worker who died of PD was assessed as having medium exposure to PQ . Lungcancer was also of interest because the initial investigation reported a modest excess (13 observed, 10.5 expected deaths).
To determine if the modest excess in polymorphism observed in deleted CNVs was due to an artefact of lower hybridisation, the relationship between sequence diversity and hybridisation signal was examined.
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