Sentence examples for modest effectiveness and from inspiring English sources

Despite modest effectiveness and considerable side effects, psychotropic drugs are frequently prescribed for these neuropsychiatric symptoms.

Orphan products are likely to have higher prices for modest effectiveness and their ICERs are expected to be higher than the cost effectiveness thresholds.

This may be due in part to the modest effectiveness and safety and tolerability issues associated with current therapeutic options, and the lack of evidence for their impact on long-term morbidity and mortality outcomes.

In vivo studies using intracranial (ic) injections of lentiviral vectors encoding PrP-specific shRNAs to knockdown focal PrPC expression [12], [13] have shown modest effectiveness experimentally and limited use clinically due to the invasive delivery method, limited area and irreversibility of PrPC suppression and safety concerns.

This conclusion about the modest effectiveness of pharmacologic and nonpharmacologic approaches might be generalized to all chronic pain conditions [ 12, 13].

First, antimetabolites, most notably methotrexate and mycophenolate mofetil, tended to be the most preferred and first used immunosuppressive agents despite only modest effectiveness, both perceived [12] and actual at least as measured by control of inflammation and corticosteroid-sparing success rates [13 15].

Prior clinical trials for diabetes and depression suggest limited reach and modest effectiveness.

This continues to occur despite their modest effectiveness, potential harms including increased risk of death and stroke, and absence of detrimental effect when people with dementia were randomised to antipsychotic withdrawal.

Influenza antiviral medications would likely be in short supply in many regions, particularly in developing countries, and might have modest effectiveness against the pandemic strain, because of the emergence of antiviral resistance or other reasons [6].

Because both RBV and Peg-IFN have modest effectiveness against HCV, at least in the first weeks of treatment, where most viruses are sensitive to PIs, 3 this dose reduction is unlikely to have a significant impact on the early viral kinetics.

They were left with a total of 20 trials that together allowed the conclusion that Tamiflu has "modest effectiveness against the symptoms of influenza in otherwise healthy adults," and that it "might be regarded as optional for reducing the symptoms of seasonal influenza"—but that "paucity of good data has undermined previous findings for oseltamivir's prevention of complications from influenza.