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But several studies comparing fasting athletes with nonfasting athletes have so far produced conflicting results, with some finding clear evidence that fasting left athletes more tired and had an adverse effect on their results while others found a modest effect at worst.
Anti-IP-10 therapy with BMS-936557 demonstrated a modest effect at inducing a response in patients with moderate-to-severe UC in this proof-of-concept study.
The modest effect at 200 μM (a 22% decrease at 5 days) was much greater at 500 μM FAC (51% decrease; p < 0.001).
The arcOGEN stage 1 GWAS is well powered to detect association with common variants of modest effect at the genome-wide significance level (eg, 90% power to detect an allelic OR of 1.25 at a SNP with frequency 0.35).
A simulation study showed that a sample size of 1000 subjects allows to obtain a power of 98% to detect a modest effect (at least 0.1 SD change) on miRNAs expression, for a 1 SD change in exposure.
Substances 0712 1 (succussed solvent) and 0712 2 (remedy) exerted a modest effect at the 1 10 dilution, which could be related to the concentration of ethanol of about 2% at this dilution level (Table 1).
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Interventions that have even quite modest effects at the individual level could drastically reduce the future burden of dementia associated with Alzheimer's disease at the population level.
Antibodies to DBL2γ only showed modest effects at very high concentrations.
19 22 Studies of LBP guideline implementation have shown no or modest effects at changing clinical practice.
Studies of low back pain guideline implementation have shown no or modest effects at changing clinical practice.
The identification of modest effects at individual low frequency and rare variants requires very large sample sizes.
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