Metformin used in overweight or obese individuals with elevated fasting glucose and impaired glucose tolerance was associated with modest but durable weight loss and was safe and well tolerated over many years.
Thus, the data providing evidence that metformin is associated with "modest, but durable weight loss" over the 10 years of treatment and appears to be safe and well tolerated cannot be overstated.
But modest monthly increases of durable and non-durable consumer goods, 0.2 and 0.1 percent respectively, suggested no inflationary pressure.
But this rural country of 30 million people, where life expectancy is only about 45 years and infant mortality is among the highest in the world, will have to adjust slowly from the boom in services and construction to something more durable and modest.
Immunomodulation has classically been considered a therapeutic strategy for RCC, and cytokine-based immunotherapeutic agents such as IL-2 are associated with modest rates of highly durable responses.
Durable enough for modest country cottages, it was meant for families on a tight budget.
It's not far from the Music Hall of Williamsburg, which used to be the more modest Northsix, or the improbably durable Thai restaurant Sea, which was an early arrival and is basically a nightclub that serves curry.
These antibodies have shown modest success independently in achieving durable responses against SR- GVHD (10 11 12 132) (10 11 12 13
Dependable and durable and small!
Moyes, now 50, had a modest playing career as a committed and durable central defender.
